Thursday, August 15, 2019
Bill Gates Speech at Harvard
President Bok, former President Rudenstine, incoming President Faust, members of the Harvard Corporation and the Board of Overseers, members of the faculty, parents, and especially, the graduates: I've been waiting more than 30 years to say this: ââ¬Å"Dad, I always told you I'd come back and get my degree. â⬠I want to thank Harvard for this honour. I'll be changing my job next year â⬠¦ and it will be nice to finally have a college degree on my resume. I applaud the graduates today for taking a much more direct route to your degrees. For my part, I'm just happy that the Crimson has called me ââ¬Å"Harvard's most successful dropout. I guess that makes me valedictorian of my own special class â⬠¦ I did the best of everyone who failed. One of my biggest memories of Harvard came in January 1975, when I made a call from Currier House to a company in Albuquerque that had begun making the world's first personal computers. I offered to sell them software. I worried that they would realise I was just a student in a dorm and hang up on me. Instead they said: ââ¬Å"We're not quite ready, come see us in a month,â⬠which was a good thing, because we hadn't written the software yet.From that moment, I worked day and night on this little extra credit project that marked the end of my college education and the beginning of a remarkable journey with Microsoft. Members of the Harvard Family: Here in the Yard is one of the great collections of intellectual talent in the world. For what purpose? There is no question that the faculty, the alumni, the students, and the benefactors of Harvard have used their power to improve the lives of people here and around the world. But can we do more?Can Harvard dedicate its intellect to improving the lives of people who will never even hear its name? Let me make a request of the deans and the professors ââ¬â the intellectual leaders here at Harvard: As you hire new faculty, award tenure, review curriculum, and determi ne degree requirements, please ask yourselves: Should our best minds be dedicated to solving our biggest problems? Should Harvard encourage its faculty to take on the world's worst inequities? Should Harvard students learn about the depth of global poverty â⬠¦ the prevalence of world hunger â⬠¦ he scarcity of clean water â⬠¦ the girls kept out of school â⬠¦ the children who die from diseases we can cure? My mother, who was filled with pride the day I was admitted here ââ¬â never stopped pressing me to do more for others.A few days before my wedding, she hosted a bridal event, at which she read aloud a letter about marriage that she had written to Melinda. My mother was very ill with cancer at the time, but she saw one more opportunity to deliver her message, and at the close of the letter she said: ââ¬Å"From those to whom much is given, much is expected. In line with the promise of this age, I want to exhort each of the graduates here to take on an issue ââ¬â a complex problem, a deep inequity, and become a specialist on it. If you make it the focus of your career, that would be phenomenal. But you don't have to do that to make an impact. For a few hours every week, you can use the growing power of the Internet to get informed, find others with the same interests, see the barriers, and find ways to cut through them. Don't let complexity stop you.Be activists. Take on the big inequities. It will be one of the great experiences of your lives. And I hope you will come back here to Harvard 30 years from now and reflect on what you have done with your talent and your energy. I hope you will judge yourselves not on your professional accomplishments alone, but also on how well you have addressed the world's deepest inequities â⬠¦ on how well you treated people a world away who have nothing in common with you but their humanity.
Wednesday, August 14, 2019
Fermentation of Yeast with Carbohydrates
Cell membranes are a bilayer make up of phospholipids, proteins, and cholesterol. Its main function is to regulate what comes in and out of the cell by means of diffusion, transport proteins and protein channels. Trans membrane proteins transport polar solutes across hydrophobic regions of the bilayer. Diffusion occurs when solutes are transferred from a high concentration of that solute to a lower concentration of solutes.Solutes do not depend on the concentration of other solutes, which allows the cell to take in oxygen while releasing carbon dioxide. Osmosis is a special type of diffusion, which occurs when water is diffused across the membrane. This can be affected by how hydrophilic a solute is on either side of the membrane. The diffusion of glucose, starch, and iodine was observed when the solutes went from a higher concentration of their individual solute to a lower concentration diffusing threw pores in the dialysis bag.The experiment sought to find out which solutes would d iffuse threw the pores of the dialysis bag, whether in or out of the bag. The pores and walls of the dialysis bag acted as a permeable membrane, like the one found in cells, and was the regulator of diffusion for the solutes. Studying the movement of solutes threw the dialysis bag helps better understand diffusion of a cell membrane, and the means and solutes that make a solution isotonic.If the iodine concentration is higher outside the dialysis bag of starch and glucose than in it, iodine along with water will diffuse into the bag while the starch remains in the dialysis bag and some glucose will diffuse out of the dialysis bag. Solution | Solute Concentration (M) | Tonicity (i. e. hypotonic)| Expected mass change (+ or -)| 1| 0. 058 M| Hypertonic| -| 2| 0. 134 M| Hypertonic | -| 3| . 000385 M| Hypotonic | +|
Tuesday, August 13, 2019
Strateget management Reflection Assignment Example | Topics and Well Written Essays - 2000 words
Strateget management Reflection - Assignment Example Needless to say, it is something every company executive must keep in mind in running their business. Quite frankly though, this is a bit of a no-brainer for me; I have been raised from birth to be responsible in all aspects of life, so strategic management isnââ¬â¢t something I am incapable of. While it is true that different people may have varying degrees of success in this regard, this will still help any business no matter what field. Case in point: all big name companies that we have known, regardless of whether they were forced to declare bankruptcy, were able to pull this off somehow else they would never have gotten off the ground. Most of us, even non-business majors, no doubt already know this. This being the case, it becomes even more important to learn this skill which will spell the difference between success and failure in our careers. In particular, three steps are most important in my opinion ââ¬â scanning both the external (knowing oneââ¬â¢s surroundings) and internal (knowing oneself) environments, as well as the competition (knowing the enemy), which will be the focus of this paper. As I heard somewhere before, only by knowing both oneself and the enemy (or in this case, competition) can success be guaranteed. According to Elisabeth Chapus et al (2010), environmental scanning, both internal and external, is meant to aid managers in making decisions and to respond adequately to weak signals coming from the environment. Coming up with plans usually entails taking into account the current situation, and strategic management is no exception. However, unlike normal planning that focuses mainly on thinking of the future, strategic management emphasizes good decision-making in order to achieve a desirable future (Craig Dobbins, 2010). To this end, managers must be able to make educated guesses about the future based on what they see now, achieving a fit in terms of how the company can
Monday, August 12, 2019
Grandparents Raising their Grandchildren Essay Example | Topics and Well Written Essays - 1750 words
Grandparents Raising their Grandchildren - Essay Example This paper discusses the difficulties, benefits, causes and other such factor related to the topic of grandparents acting as parent to their grandchildren. Grandparents who raise their grandchildren have become prevalent as an alternative family.(Bert, 2005) It is reported that 5.7 million children are living with their grandparents out of which 3.7 million live in grandparents household. Various factsheets reveal that there thousands of grandparents in United States taking care of their grandchildren due to numerous reasons. It is not an easy task to identify the exact number of grandparents raising their grandchildren without a parent due to informal relationships. With rising divorces, death of parents, disability, inability to care for their children, have increased the number of grandchildren being raised by grandparents. Kleiner et. al (1998) has classified grandparents into three sub groups as custodial grandparents, caregivers and day care parents. Casper & Bryson (1998) Custodial grand parenting is growing trend in American society with some 5.5 million grandparents have reported to be housing their own grandchildren in the year 1997. (Bert, 2005) It is also reported that the ages of most of the grandparents are between 55 and 64 years and 20% are over 65 years. Caregiver is explained as 'living with' grandparents who provide daily care but do not have legal custody. In such cases, grandparents focus on providing the child with economically and emotionally stable environment. The another classification 'day care' grandparents focus on helping the child's parent and function closest to societal function of grandparent. Causes for Grandparents Acting as Grandparents According to American Community Survey, 6.1 million grandparents are engaged in parenting activity in respect to their grandchild. 8% of grandchildren lived with their grandparent in the year 2006 in United States. (US Census Bureau, 2006) Grandparent after retiring from parenting activities after their child has settled well, if resumes the parenting job again, it needs a lot of careful thinking on the topic. Grandparents usually accept the task out of natural love and affection towards their grandchildren and would not accept the role of stranger in raising their grandchildren. (www.cornellcares.org) Most of the causes would revolve around the normal parents. Most of the statistics reveal that drug or alcohol abuse among natural parents is the main cause for inviting grandparent to step in and take over the responsibility of raising their grandchildren. It has been reported that in 1998 nearly 44% of youngsters were living with their grandparents because of their parents' substance abuse. And interestingly 28% were victims of child abuse, neglect or improper attention and 11% because of death of their any one or both of the parents. (www.egyptianaaa.org) Various reasons include ill health of their parents, or inability of parents to take the responsibility of their child, divorce, unexpected pregnancy of teen or adult child, etc. The reasons why the grandparents are acting as parents may vary on various factors. Difficulties of Grandparents to raise their child Many researches have been
Sunday, August 11, 2019
Drug use in college students Assignment Example | Topics and Well Written Essays - 500 words
Drug use in college students - Assignment Example There are many dependent variables out of which, level of drug use is explained here. Level of drug use can be described as usage level of illegal drugs by the students whether they are using the drugs by habit or as per social constraints (Riley, 2012). The level of drug use has many possible attributes such as intensity of consumption of drugs resulting in falling health, which also affects the studies of the student. Illegal drug usage by students is a thought provoking concern and should be dealt considerably by law enforcement officials in order to control the issue. The independent variables related to drug use in college students can be attachment, commitment and level of college involvement (Riley, 2012). Students studying in colleges form attachment with their close people and places such as parents, school and college mates. The independent variable of attachment has attributes such as level of affection, respect of the elders and deterrence to use drugs. Attachment with any person or place appears as a force stopping students to use illegal drugs (Riley, 2012). Commitment is another independent variable that has many attributes such as studentsââ¬â¢ reputation in the college, employment of students and religion that they follow. All these attributes affect the students in being committed to their set values due to which, they are restricted to the drug usage in colleges (Riley, 2012). By considering their commitments to various options available to students, they are hindered to make illegal drug usage that is beneficial for their career and health. The level of college involvement is an independent variable, which can be explained as being engaged in co-curricular activities such as games, club memberships, employment and fraternities and much more. These engagements hinder the college students to get indulged in drug usage considering
Saturday, August 10, 2019
Marine Ship Yard Research Paper Example | Topics and Well Written Essays - 1000 words
Marine Ship Yard - Research Paper Example It has negative impacts on many shipbuilding companies and counties around the world due to the biggest overcapacity of shipyards such as the far greater supply of fleet that it requires by the market (Mickeviciene). In order to meet the market and business success Western Marine Shipyard must consider that different countries have many nationalities that help the company to bring new ideas and ways to enhance the continuous strive to business success. Employees should be empowered in order to seek new opportunities, innovate and build an efficient working environment that is professional and positive for all. Western Marine Shipyard team members undergo intensive training to have a quality service and produce highly products and, the company considers it is a career, a great opportunity to work among the best personnel, receive the support needed to the make good decisions and deliver the best outcomes. This will carry out into the different branches around the world. In terms its benefits and financial impact, the recommendation will hit hard the shipyards. The primary challenge is in the industry is intermediate financing and this challenge having direct impact on the industrys production cos t, quality and growth. On the positive note the government should support its shipbuilding industry. The western Marine shipyard will be continually challenged with inconsistencies/contradiction - deal with the changes because the management is the integrating force within the organizationââ¬â¢s activities. Whenever two or more individual works together in order to achieve a common goal, they have to communicate or coordinate their activities or programs. The employees also should be organized and maximize their resources in such way as to optimize the outcomes. The company will face with the challenge to manage both stability and change within organizations in the future. This has been evident in the story of
Gleevac Essay Example | Topics and Well Written Essays - 3000 words
Gleevac - Essay Example It has four pKa values; 1.52, 2.56, 3.73, 8.07, very soluble in buffers of PH 5.5 and slightly soluble in neutral/alkaline aqueous buffers. Gleevec recognizes the auto inhibitory conformation of the activation loop of the protein that regulates the kinase activity. The structure of inactive state is distinct between different kinases. It has a half-life of 15 hours and allows daily administration. Gleevec is used to treat the chronic phase of CML though applications have been found in Advanced and blast crisis phases. Its efficacy has been found to reduce with phase progression.Most patients that donââ¬â¢t respond to gleevec are in advanced stages of CML at the initiation of treatment. Failure rate of imatinib in patient with chronic phase CML remains low(at less than 15%at 18 months) in patients who did not respond to interferon. In the 1980ââ¬â¢s and 90ââ¬â¢s much skepticism prevailed first on the development of compounds with specificity among protein kinases. Secondly, the targeting of singular molecular defects seemed insufficient in the treatment of highly heterogeneous cancer [11]. Gazit in 1989 reported low molecular weight tyrosine kinase inhibitors with selective activity towards EGFR. These inhibitors were called tyrophostins. Tyrophostins were useful in selective antiproliferation agents for proliferative diseases caused by hyperactivity of protein tyrosine kinases. Though tyrophostins were not clinically developed, they provided the proof of the principle of selective inhibition of tyrosine kinases by using small molecules [16]. Subsequently 2 phenylaminopyrimidines were reported as selective inhibitors for protein kinases C (PKC), Abelson (ABL) and platelet derived growth factor receptor (PDGFR) kinases [3]. Tyrosine kinases mediate many of the signaling pathways by which cancer cells prom ote their proliferation and survival. They control cellular function and are thought to be too similar to be inhibited in-vivo [15]. Overall imatinib shows
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